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Beneficial effects of β-sitosterol on type 1 cholecystokinin receptor dysfunction induced by elevated membrane cholesterol

BACKGROUND & AIMS: The type 1 cholecystokinin receptor (CCK1R) mediates the actions of CCK to support nutritional homeostasis, including post-cibal satiety. However, elevated levels of membrane cholesterol, such as have been observed in metabolic syndrome, interfere with CCK stimulus-activity co...

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Vydáno v:Clin Nutr
Hlavní autoři: Desai, Aditya J., Dong, Maoqing, Miller, Laurence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025326/
https://ncbi.nlm.nih.gov/pubmed/27016394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clnu.2016.03.003
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