Tetraspanin 8 (TSPAN8) mediates AEG-1-induced invasion and metastasis in hepatocellular carcinoma (HCC) cells

Astrocyte elevated gene-1 (AEG-1) positively regulates tumor progression and metastasis. Here we document that AEG-1 upregulates transcription of the membrane protein tetraspanin8 (TSPAN8). Knocking down TSPAN8 in AEG-1-overexpressing human hepatocellular carcinoma (HCC) cells markedly inhibited inv...

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Detaylı Bibliyografya
Yayımlandı:FEBS Lett
Asıl Yazarlar: Akiel, Maaged A., Santhekadur, Prasanna K., Mendoza, Rachel G., Siddiq, Ayesha, Fisher, Paul B., Sarkar, Devanand
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992437/
https://ncbi.nlm.nih.gov/pubmed/27339400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12268
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