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Tetraspanin 8 (TSPAN8) mediates AEG-1-induced invasion and metastasis in hepatocellular carcinoma (HCC) cells
Astrocyte elevated gene-1 (AEG-1) positively regulates tumor progression and metastasis. Here we document that AEG-1 upregulates transcription of the membrane protein tetraspanin8 (TSPAN8). Knocking down TSPAN8 in AEG-1-overexpressing human hepatocellular carcinoma (HCC) cells markedly inhibited inv...
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| Publicat a: | FEBS Lett |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992437/ https://ncbi.nlm.nih.gov/pubmed/27339400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12268 |
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