Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC)

Non-thyroidal illness syndrome (NTIS), characterized by low serum 3,5,3′-triiodothyronine (T(3)) with normal l-thyroxine (T(4)) levels, is associated with malignancy. Decreased activity of type I 5′-deiodinase (DIO1), which converts T(4) to T(3), contributes to NTIS. T(3) binds to thyroid hormone re...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Srivastava, Jyoti, Robertson, Chadia L., Gredler, Rachel, Siddiq, Ayesha, Rajasekaran, Devaraja, Akiel, Maaged A., Emdad, Luni, Mas, Valeria, Mukhopadhyay, Nitai D., Fisher, Paul B., Sarkar, Devanand
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505468/
https://ncbi.nlm.nih.gov/pubmed/25944909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649707
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