Genetic deletion of AEG-1 prevents hepatocarcinogenesis

Activation of the oncogene AEG-1 (MTDH, LYRIC) has been implicated recently in the development of hepatocellular carcinoma (HCC). In mice, HCC can be initiated by exposure to the carcinogen DEN, which has been shown to rely upon activation of NF-κB in liver macrophages. Since AEG-1 is an essential c...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Robertson, Chadia L., Srivastava, Jyoti, Siddiq, Ayesha, Gredler, Rachel, Emdad, Luni, Rajasekaran, Devaraja, Akiel, Maaged, Shen, Xue-Ning, Guo, Chunqing, Giashuddin, Shah, Wang, Xiang-Yang, Ghosh, Shobha, Subler, Mark A, Windle, Jolene J., Fisher, Paul B., Sarkar, Devanand
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216744/
https://ncbi.nlm.nih.gov/pubmed/25193383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1357
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы