Genetic deletion of AEG-1 prevents hepatocarcinogenesis

Activation of the oncogene AEG-1 (MTDH, LYRIC) has been implicated recently in the development of hepatocellular carcinoma (HCC). In mice, HCC can be initiated by exposure to the carcinogen DEN, which has been shown to rely upon activation of NF-κB in liver macrophages. Since AEG-1 is an essential c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Robertson, Chadia L., Srivastava, Jyoti, Siddiq, Ayesha, Gredler, Rachel, Emdad, Luni, Rajasekaran, Devaraja, Akiel, Maaged, Shen, Xue-Ning, Guo, Chunqing, Giashuddin, Shah, Wang, Xiang-Yang, Ghosh, Shobha, Subler, Mark A, Windle, Jolene J., Fisher, Paul B., Sarkar, Devanand
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216744/
https://ncbi.nlm.nih.gov/pubmed/25193383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1357
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