Genetic deletion of AEG-1 prevents hepatocarcinogenesis

Activation of the oncogene AEG-1 (MTDH, LYRIC) has been implicated recently in the development of hepatocellular carcinoma (HCC). In mice, HCC can be initiated by exposure to the carcinogen DEN, which has been shown to rely upon activation of NF-κB in liver macrophages. Since AEG-1 is an essential c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Robertson, Chadia L., Srivastava, Jyoti, Siddiq, Ayesha, Gredler, Rachel, Emdad, Luni, Rajasekaran, Devaraja, Akiel, Maaged, Shen, Xue-Ning, Guo, Chunqing, Giashuddin, Shah, Wang, Xiang-Yang, Ghosh, Shobha, Subler, Mark A, Windle, Jolene J., Fisher, Paul B., Sarkar, Devanand
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216744/
https://ncbi.nlm.nih.gov/pubmed/25193383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1357
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