טוען...
Essential roles for Polymerase θ mediated end-joining in repair of chromosome breaks
DNA Polymerase theta (Pol θ) mediated end-joining (TMEJ) has been implicated in repair of chromosome breaks, but its cellular mechanism and role relative to canonical repair pathways is poorly understood. We show it accounts for most repair associated with microhomologies, and is made efficient by c...
שמור ב:
| הוצא לאור ב: | Mol Cell |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992412/ https://ncbi.nlm.nih.gov/pubmed/27453047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.06.020 |
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