Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

The role of IL10 in the tumorigenesis of various cancer types is still controversial. Here, we found that increased IL10 levels are correlated with a poor prognosis in lung cancer patients. Moreover, IL10 levels were significantly increased in the lungs and serum of EGFR(L858R)- and Kras4b(G12D)-ind...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Hsu, Tsung-I, Wang, Yi-Chang, Hung, Chia-Yang, Yu, Chun-Hui, Su, Wu-Chou, Chang, Wen-Chang, Hung, Jan-Jong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991496/
https://ncbi.nlm.nih.gov/pubmed/26956044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7894
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