Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

The role of IL10 in the tumorigenesis of various cancer types is still controversial. Here, we found that increased IL10 levels are correlated with a poor prognosis in lung cancer patients. Moreover, IL10 levels were significantly increased in the lungs and serum of EGFR(L858R)- and Kras4b(G12D)-ind...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Hsu, Tsung-I, Wang, Yi-Chang, Hung, Chia-Yang, Yu, Chun-Hui, Su, Wu-Chou, Chang, Wen-Chang, Hung, Jan-Jong
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991496/
https://ncbi.nlm.nih.gov/pubmed/26956044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7894
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