Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

In this study, we found that Sp1 was highly expressed in astrocytes, implying that Sp1 might be important for the function of astrocytes. Sp1/GFAP-Cre-ERT2 conditional knockout mice were constructed to study the role of Sp1 in astrocytes. Knockout of Sp1 in astrocytes altered astrocytic morphology a...

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Udgivet i:Mol Neurobiol
Main Authors: Hung, Chia-Yang, Hsu, Tsung-I, Chuang, Jian-Ying, Su, Tsung-Ping, Chang, Wen-Chang, Hung, Jan-Jong
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269153/
https://ncbi.nlm.nih.gov/pubmed/31317491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01694-7
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