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Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression

Rationale: Brain metastasis in patients with lung cancer is life-threatening. However, the molecular mechanism for this catastrophic disease remains elusive, and few druggable targets are available. Therefore, this study aimed to identify and characterize proteins that could be used as therapeutic t...

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Veröffentlicht in:Theranostics
Hauptverfasser: Lin, Ching-Chan, Huang, Yu-Kai, Cho, Chia-Fong, Lin, Yu-Sen, Lo, Chia-Chien, Kuo, Ting-Ting, Tseng, Guan-Chin, Cheng, Wei-Chung, Chang, Wei-Chao, Hsiao, Tzu-Hung, Lai, Liang-Chuan, Shih, Jin-Yuan, Liu, Yu-Huei, Chao, K.S. Clifford, Hsu, Jennifer L., Lee, Pei-Chih, Sun, Xian, Hung, Mien-Chie, Sher, Yuh-Pyng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532684/
https://ncbi.nlm.nih.gov/pubmed/33042262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49425
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