Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

The metastatic cascade describes the escape of primary tumour cells to distant secondary sites. Cells at the leading tumour edge are thought to undergo epithelial-mesenchymal transition (EMT), to enhance their motility and invasion for spreading. Whether EMT cells directly promote tumour angiogenesi...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Gopal, Shashi K., Greening, David W., Hanssen, Eric G., Zhu, Hong-Jian, Simpson, Richard J., Mathias, Rommel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991413/
https://ncbi.nlm.nih.gov/pubmed/26919098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7573
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