Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis

Epithelial-mesenchymal transition (EMT) enhances the migration and invasion of cancer cells, and is regulated by various molecular mechanisms including extracellular matrix metalloproteinase (MMP) activity. Previously, we reported transformation of epithelial Madin-Darby canine kidney (MDCK) cells w...

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Vydáno v:Sci Rep
Hlavní autoři: Gopal, Shashi K., Greening, David W., Zhu, Hong-Jian, Simpson, Richard J., Mathias, Rommel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914959/
https://ncbi.nlm.nih.gov/pubmed/27324842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28321
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