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Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis

Epithelial-mesenchymal transition (EMT) enhances the migration and invasion of cancer cells, and is regulated by various molecular mechanisms including extracellular matrix metalloproteinase (MMP) activity. Previously, we reported transformation of epithelial Madin-Darby canine kidney (MDCK) cells w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gopal, Shashi K., Greening, David W., Zhu, Hong-Jian, Simpson, Richard J., Mathias, Rommel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914959/
https://ncbi.nlm.nih.gov/pubmed/27324842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28321
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