Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

ErbB3, a member of the ErbB family receptors, has a key role in the development and progression of several cancers, including non-small cell lung cancer (NSCLC), and in the establishment of resistance to therapies, leading to the development of anti-ErbB3 therapies. In this study we demonstrated, in...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Ciardiello, Chiara, Roca, Maria Serena, Noto, Alessia, Bruzzese, Francesca, Moccia, Tania, Vitagliano, Carlo, Gennaro, Elena Di, Ciliberto, Gennaro, Roscilli, Giuseppe, Aurisicchio, Luigi, Marra, Emanuele, Mancini, Rita, Budillon, Alfredo, Leone, Alessandra
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991401/
https://ncbi.nlm.nih.gov/pubmed/26862736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7195
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