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A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain
Factor XI (FXI) is the zymogen of FXIa, which cleaves FIX in the intrinsic pathway of coagulation. FXI is known to exist as a dimer and interacts with multiple proteins via its 4 apple domains in the “saucer section” of the enzyme; however, to date, no complex crystal structure has been described. T...
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| Publicat a: | Blood |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4991086/ https://ncbi.nlm.nih.gov/pubmed/27006387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-676122 |
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