A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium

PURPOSE: Noncoding microRNAs (miRNAs) have been implicated in the pathogenesis of glaucoma. We aimed to identify common variants in miRNA coding genes (MIR) associated with primary open-angle glaucoma (POAG). METHODS: Using the NEIGHBORHOOD data set (3853 cases/33,480 controls with European ancestry...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Liu, Yutao, Bailey, Jessica Cooke, Helwa, Inas, Dismuke, W. Michael, Cai, Jingwen, Drewry, Michelle, Brilliant, Murray H., Budenz, Donald L., Christen, William G., Chasman, Daniel I., Fingert, John H., Gaasterland, Douglas, Gaasterland, Terry, Gordon, Mae O., Igo, Robert P., Kang, Jae H., Kass, Michael A., Kraft, Peter, Lee, Richard K., Lichter, Paul, Moroi, Sayoko E., Realini, Anthony, Richards, Julia E., Ritch, Robert, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Song, Yeunjoo E., Vollrath, Douglas, Weinreb, Robert, Medeiros, Felipe, Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Pericak-Vance, Margaret A., Gonzalez, Pedro, Stamer, W. Daniel, Kuchtey, John, Kuchtey, Rachel W., Allingham, R. Rand, Hauser, Michael A., Pasquale, Louis R., Haines, Jonathan L., Wiggs, Janey L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991020/
https://ncbi.nlm.nih.gov/pubmed/27537254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19688
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