Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis

IMPORTANCE: Genetic variants associated with primary open-angle glaucoma (POAG) are known to influence disease risk. However, the clinical effect of associated variants individually or in aggregate is not known. Genetic risk scores (GRS) examine the cumulative genetic load by combining individual ge...

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Detalhes bibliográficos
Publicado no:JAMA Ophthalmol
Main Authors: Fan, Bao Jian, Bailey, Jessica Cooke, Igo, Rob P., Kang, Jae H., Boumenna, Tahani, Brilliant, Murray H., Budenz, Donald L., Fingert, John H., Gaasterland, Terry, Gaasterland, Douglas, Hauser, Michael A., Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Moroi, Syoko E., Myers, Jonathan S., Pericak-Vance, Margaret A., Realini, Anthony, Rhee, Douglas J., Richards, Julia E., Ritch, Robert, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Weinreb, Robert N., Wollstein, Gadi, Zack, Donald J., Haines, Jonathan L., Pasquale, Louis R., Wiggs, Janey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707005/
https://ncbi.nlm.nih.gov/pubmed/31436842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2019.3109
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