Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses

PURPOSE: Recent studies indicate that mitochondrial proteins may contribute to the pathogenesis of primary open-angle glaucoma (POAG). In this study, we examined the association between POAG and common variations in gene-encoding mitochondrial proteins. METHODS: We examined genetic data from 3430 PO...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Khawaja, Anthony P., Cooke Bailey, Jessica N., Kang, Jae Hee, Allingham, R. Rand, Hauser, Michael A., Brilliant, Murray, Budenz, Donald L., Christen, William G., Fingert, John, Gaasterland, Douglas, Gaasterland, Terry, Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Medeiros, Felipe, Moroi, Syoko E., Richards, Julia E., Realini, Tony, Ritch, Robert, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Pericak-Vance, Margaret, Weinreb, Robert N., Haines, Jonathan L., Pasquale, Louis R., Wiggs, Janey L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040191/
https://ncbi.nlm.nih.gov/pubmed/27661856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20017
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