Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Activation of purinergic receptors in the spinal cord by extracellular ATP is essential for neuropathic hypersensitivity after peripheral nerve injury (PNI). However, the cell type responsible for releasing ATP within the spinal cord after PNI is unknown. Here we show that PNI increases expression o...

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發表在:Nat Commun
Main Authors: Masuda, Takahiro, Ozono, Yui, Mikuriya, Satsuki, Kohro, Yuta, Tozaki-Saitoh, Hidetoshi, Iwatsuki, Ken, Uneyama, Hisayuki, Ichikawa, Reiko, Salter, Michael W., Tsuda, Makoto, Inoue, Kazuhide
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990655/
https://ncbi.nlm.nih.gov/pubmed/27515581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12529
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