Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Activation of purinergic receptors in the spinal cord by extracellular ATP is essential for neuropathic hypersensitivity after peripheral nerve injury (PNI). However, the cell type responsible for releasing ATP within the spinal cord after PNI is unknown. Here we show that PNI increases expression o...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Masuda, Takahiro, Ozono, Yui, Mikuriya, Satsuki, Kohro, Yuta, Tozaki-Saitoh, Hidetoshi, Iwatsuki, Ken, Uneyama, Hisayuki, Ichikawa, Reiko, Salter, Michael W., Tsuda, Makoto, Inoue, Kazuhide
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990655/
https://ncbi.nlm.nih.gov/pubmed/27515581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12529
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