Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Activation of purinergic receptors in the spinal cord by extracellular ATP is essential for neuropathic hypersensitivity after peripheral nerve injury (PNI). However, the cell type responsible for releasing ATP within the spinal cord after PNI is unknown. Here we show that PNI increases expression o...

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Publicado en:Nat Commun
Main Authors: Masuda, Takahiro, Ozono, Yui, Mikuriya, Satsuki, Kohro, Yuta, Tozaki-Saitoh, Hidetoshi, Iwatsuki, Ken, Uneyama, Hisayuki, Ichikawa, Reiko, Salter, Michael W., Tsuda, Makoto, Inoue, Kazuhide
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990655/
https://ncbi.nlm.nih.gov/pubmed/27515581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12529
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