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Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma

PURPOSE: Brn3b is a class IV POU domain transcription factor that plays an important role in the development of retinal ganglion cells (RGCs), RGC survival, and particularly axon growth and pathfinding. Our previous study demonstrated that recombinant adenoassociated virus serotype 2 (rAAV-2)–mediat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Vis
Päätekijät: Phatak, Nitasha R., Stankowska, Dorota L., Krishnamoorthy, Raghu R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Molecular Vision 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990101/
https://ncbi.nlm.nih.gov/pubmed/27587945
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