Neuroprotective Effects of Transcription Factor Brn3b in an Ocular Hypertension Rat Model of Glaucoma

PURPOSE. Glaucoma is an optic neuropathy commonly associated with elevated intraocular pressure (IOP), leading to optic nerve head (ONH) cupping, axon loss, and apoptosis of retinal ganglion cells (RGCs), which could ultimately result in blindness. Brn3b is a class-4 POU domain transcription factor...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Stankowska, Dorota L., Minton, Alena Z., Rutledge, Margaret A., Mueller, Brett H., Phatak, Nitasha R., He, Shaoqing, Ma, Hai-Ying, Forster, Michael J., Yorio, Thomas, Krishnamoorthy, Raghu R.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321399/
https://ncbi.nlm.nih.gov/pubmed/25587060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15008
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