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Neuroprotective Effects of Transcription Factor Brn3b in an Ocular Hypertension Rat Model of Glaucoma

PURPOSE. Glaucoma is an optic neuropathy commonly associated with elevated intraocular pressure (IOP), leading to optic nerve head (ONH) cupping, axon loss, and apoptosis of retinal ganglion cells (RGCs), which could ultimately result in blindness. Brn3b is a class-4 POU domain transcription factor...

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書誌詳細
出版年:Invest Ophthalmol Vis Sci
主要な著者: Stankowska, Dorota L., Minton, Alena Z., Rutledge, Margaret A., Mueller, Brett H., Phatak, Nitasha R., He, Shaoqing, Ma, Hai-Ying, Forster, Michael J., Yorio, Thomas, Krishnamoorthy, Raghu R.
フォーマット: Artigo
言語:Inglês
出版事項: The Association for Research in Vision and Ophthalmology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321399/
https://ncbi.nlm.nih.gov/pubmed/25587060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15008
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