Neuroprotective Effects of Transcription Factor Brn3b in an Ocular Hypertension Rat Model of Glaucoma

PURPOSE. Glaucoma is an optic neuropathy commonly associated with elevated intraocular pressure (IOP), leading to optic nerve head (ONH) cupping, axon loss, and apoptosis of retinal ganglion cells (RGCs), which could ultimately result in blindness. Brn3b is a class-4 POU domain transcription factor...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Stankowska, Dorota L., Minton, Alena Z., Rutledge, Margaret A., Mueller, Brett H., Phatak, Nitasha R., He, Shaoqing, Ma, Hai-Ying, Forster, Michael J., Yorio, Thomas, Krishnamoorthy, Raghu R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321399/
https://ncbi.nlm.nih.gov/pubmed/25587060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15008
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