Endothelin B Receptors Contribute to Retinal Ganglion Cell Loss in a Rat Model of Glaucoma

Glaucoma is an optic neuropathy, commonly associated with elevated intraocular pressure (IOP) characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells which could lead to loss of vision. Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide that pl...

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Hauptverfasser: Minton, Alena Z., Phatak, Nitasha R., Stankowska, Dorota L., He, Shaoqing, Ma, Hai-Ying, Mueller, Brett H., Jiang, Ming, Luedtke, Robert, Yang, Shaohua, Brownlee, Colby, Krishnamoorthy, Raghu R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423444/
https://ncbi.nlm.nih.gov/pubmed/22916224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043199
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