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Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells
PURPOSE: The goal of this study was to determine whether JNK2 played a causative role in endothelin-mediated loss of RGCs in mice. METHODS: JNK2(−/−) and wild type (C57BL/6) mice were intravitreally injected in one eye with 1 nmole of ET-1, whereas the contralateral eye was injected with the vehicle...
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| 發表在: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Association for Research in Vision and Ophthalmology
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131991/ https://ncbi.nlm.nih.gov/pubmed/33978676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.6.13 |
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