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Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation

Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs), the output neurons of the retina. Multiple lines of evidence show the endothelin (EDN, also known as ET) system is important in glaucomatous neurodegeneration. To date, the molecular mechanisms within RGC...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Marola, Olivia J., Syc-Mazurek, Stephanie B., Howell, Gareth R., Libby, Richard T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519907/
https://ncbi.nlm.nih.gov/pubmed/32980857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02990-0
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