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Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation

Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs), the output neurons of the retina. Multiple lines of evidence show the endothelin (EDN, also known as ET) system is important in glaucomatous neurodegeneration. To date, the molecular mechanisms within RGC...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Marola, Olivia J., Syc-Mazurek, Stephanie B., Howell, Gareth R., Libby, Richard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519907/
https://ncbi.nlm.nih.gov/pubmed/32980857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02990-0
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