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JUN is important for ocular hypertension-induced retinal ganglion cell degeneration

Ocular hypertension, a major risk factor for glaucoma, is thought to trigger glaucomatous neurodegeneration through injury to retinal ganglion cell (RGC) axons. The molecular signaling pathway leading from ocular hypertension to RGC degeneration, however, is not well defined. JNK signaling, a compon...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Syc-Mazurek, Stephanie B, Fernandes, Kimberly A, Libby, Richard T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550879/
https://ncbi.nlm.nih.gov/pubmed/28726785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.338
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