JUN is important for ocular hypertension-induced retinal ganglion cell degeneration

Ocular hypertension, a major risk factor for glaucoma, is thought to trigger glaucomatous neurodegeneration through injury to retinal ganglion cell (RGC) axons. The molecular signaling pathway leading from ocular hypertension to RGC degeneration, however, is not well defined. JNK signaling, a compon...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Syc-Mazurek, Stephanie B, Fernandes, Kimberly A, Libby, Richard T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550879/
https://ncbi.nlm.nih.gov/pubmed/28726785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.338
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