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ΔN-Bcl-xL, a therapeutic target for neuroprotection
The B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial anti-apoptotic protein that plays a role in neuroprotection. However, during excitotoxic stimulation, Bcl-xL undergoes caspase-dependent cleavage and produces a fragmented form, ΔN-Bcl-xL. Accumulation of ΔN-Bcl-xL is associated with mitoch...
Sparad:
| I publikationen: | Neural Regen Res |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Medknow Publications & Media Pvt Ltd
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745825/ https://ncbi.nlm.nih.gov/pubmed/29239317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.219033 |
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