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Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis

Mycolic acids are indispensible lipids of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), and contribute to the distinctive architecture and impermeability of the mycobacterial cell envelope. FadD32 plays a pivotal role in mycolic acid biosynthesis by functionally linking...

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Publicado en:ACS Infect Dis
Main Authors: Kuhn, Misty L., Alexander, Evan, Minasov, George, Page, Holland J., Warwrzak, Zdzislaw, Shuvalova, Ludmilla, Flores, Kristin J., Wilson, Daniel J., Shi, Ce, Aldrich, Courtney C., Anderson, Wayne F.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989915/
https://ncbi.nlm.nih.gov/pubmed/27547819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00082
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