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Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm

BACKGROUND: Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification. However, it is not fully understood how individual stem cells exit the pluripotent state and transition towards their respective...

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Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Chu, Li-Fang, Leng, Ning, Zhang, Jue, Hou, Zhonggang, Mamott, Daniel, Vereide, David T., Choi, Jeea, Kendziorski, Christina, Stewart, Ron, Thomson, James A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989499/
https://ncbi.nlm.nih.gov/pubmed/27534536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1033-x
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