Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm

BACKGROUND: Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification. However, it is not fully understood how individual stem cells exit the pluripotent state and transition towards their respective...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Chu, Li-Fang, Leng, Ning, Zhang, Jue, Hou, Zhonggang, Mamott, Daniel, Vereide, David T., Choi, Jeea, Kendziorski, Christina, Stewart, Ron, Thomson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989499/
https://ncbi.nlm.nih.gov/pubmed/27534536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1033-x
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