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An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells

Defects in somitogenesis result in vertebral malformations at birth known as spondylocostal dysostosis (SCDO). Somites are formed with a species-specific periodicity controlled by the “segmentation clock,” which comprises a group of oscillatory genes in the presomitic mesoderm. Here, we report that...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chu, Li-Fang, Mamott, Daniel, Ni, Zijian, Bacher, Rhonda, Liu, Cathy, Swanson, Scott, Kendziorski, Christina, Stewart, Ron, Thomson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814198/
https://ncbi.nlm.nih.gov/pubmed/31461642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.090
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