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Amyloid β oligomers elicit mitochondrial transport defects and fragmentation in a time-dependent and pathway-specific manner

Small oligomeric forms of amyloid-β (Aβ) are believed to be the culprit for declined brain functions in AD in part through their impairment of neuronal trafficking and synaptic functions. However, the precise cellular actions of Aβ oligomers and underlying mechanisms in neurons remain to be fully de...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Rui, Yanfang, Zheng, James Q.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989350/
https://ncbi.nlm.nih.gov/pubmed/27535553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0261-z
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