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Amyloid β oligomers elicit mitochondrial transport defects and fragmentation in a time-dependent and pathway-specific manner

Small oligomeric forms of amyloid-β (Aβ) are believed to be the culprit for declined brain functions in AD in part through their impairment of neuronal trafficking and synaptic functions. However, the precise cellular actions of Aβ oligomers and underlying mechanisms in neurons remain to be fully de...

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Publicado en:Mol Brain
Autores principales: Rui, Yanfang, Zheng, James Q.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989350/
https://ncbi.nlm.nih.gov/pubmed/27535553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0261-z
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