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A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects

For region-based sequencing data, power to detect genetic associations can be improved through analysis of multiple related phenotypes. With this motivation, we propose a novel test to detect association simultaneously between a set of rare variants, such as those obtained by sequencing in a small g...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Eur J Hum Genet
Main Authors: Sun, Jianping, Oualkacha, Karim, Forgetta, Vincenzo, Zheng, Hou-Feng, Brent Richards, J, Ciampi, Antonio, Greenwood, Celia MT
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989219/
https://ncbi.nlm.nih.gov/pubmed/26860061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.8
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