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Pathway analysis for genetic association studies: to do, or not to do? That is the question
In Genetic Analysis Workshop 18 data, we used a 3-stage approach to explore the benefits of pathway analysis in improving a model to predict 2 diastolic blood pressure phenotypes as a function of genetic variation. At stage 1, gene-based tests of association in family data of approximately 800 indiv...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144468/ https://ncbi.nlm.nih.gov/pubmed/25519357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S103 |
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