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HIV and Cocaine Impact Glial Metabolism: Energy Sensor AMP-activated protein kinase Role in Mitochondrial Biogenesis and Epigenetic Remodeling

HIV infection and cocaine use have been identified as risk factors for triggering neuronal dysfunction. In the central nervous system (CNS), energy resource and metabolic function are regulated by astroglia. Glia is the major reservoir of HIV infection and disease progression in CNS. However, the ro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Samikkannu, Thangavel, Atluri, Venkata S. R., Nair, Madhavan P. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989157/
https://ncbi.nlm.nih.gov/pubmed/27535703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31784
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