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HIV and Cocaine Impact Glial Metabolism: Energy Sensor AMP-activated protein kinase Role in Mitochondrial Biogenesis and Epigenetic Remodeling

HIV infection and cocaine use have been identified as risk factors for triggering neuronal dysfunction. In the central nervous system (CNS), energy resource and metabolic function are regulated by astroglia. Glia is the major reservoir of HIV infection and disease progression in CNS. However, the ro...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Samikkannu, Thangavel, Atluri, Venkata S. R., Nair, Madhavan P. N.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989157/
https://ncbi.nlm.nih.gov/pubmed/27535703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31784
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