The AIM2-like receptors are dispensable for the interferon response to intracellular DNA

Detection of intracellular DNA triggers activation of the STING-dependent interferon-stimulatory DNA (ISD) pathway, which is essential for antiviral responses. Multiple DNA sensors have been proposed to activate this pathway, including AIM2-like receptors (ALRs). Whether the ALRs are essential for a...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Gray, Elizabeth E., Winship, Damion, Snyder, Jessica M., Child, Stephanie J., Geballe, Adam P., Stetson, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988931/
https://ncbi.nlm.nih.gov/pubmed/27496731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.06.015
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