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Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
Innate immune detection of nucleic acids is important for initiation of antiviral responses. Detection of intracellular DNA activates STING-dependent type I interferons (IFNs) and the ASC-dependent inflammasome. Certain members of the AIM2-like receptor (ALR) gene family contribute to each of these...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478938/ https://ncbi.nlm.nih.gov/pubmed/23045604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121960 |
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