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Binding and Relocalization of Protein Kinase R by Murine Cytomegalovirus

Many viruses have evolved mechanisms to evade the repression of translation mediated by protein kinase R (PKR). In the case of murine cytomegalovirus (MCMV), the protein products of two essential genes, m142 and m143, bind to double-stranded RNA (dsRNA) and block phosphorylation of PKR and eukaryoti...

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Detalhes bibliográficos
Main Authors: Child, Stephanie J., Geballe, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643750/
https://ncbi.nlm.nih.gov/pubmed/19073740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01484-08
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