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Thrombospondin-4 divergently regulates voltage gated Ca(2+) channel subtypes in sensory neurons after nerve injury
Loss of high-voltage–activated (HVA) calcium current (I(Ca)) and gain of low-voltage–activated (LVA) I(Ca) after painful peripheral nerve injury cause elevated excitability in sensory neurons. Nerve injury is also accompanied by increased expression of the extracellular matrix glycoprotein thrombosp...
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| Veröffentlicht in: | Pain |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988923/ https://ncbi.nlm.nih.gov/pubmed/27168360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000612 |
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