Divergent Effects of Painful Nerve Injury on Mitochondrial Ca(2+) Buffering in Axotomized and Adjacent Sensory Neurons

Mitochondria critically regulate cytoplasmic Ca(2+) concentration ([Ca(2+)](c)), but the effects of sensory neuron injury have not been examined. Using FCCP (1μM) to eliminate mitochondrial Ca(2+) uptake combined with oligomycin (10μM) to prevent ATP depletion, we first identified features of depola...

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Gepubliceerd in:Brain Res
Hoofdauteurs: Hogan, Quinn H., Sprick, Chelsea, Guo, Yuan, Mueller, Samantha, Bienengraeber, Martin, Pan, Bin, Wu, Hsiang-En
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254330/
https://ncbi.nlm.nih.gov/pubmed/25251590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.09.040
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