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Thrombospondin-4 divergently regulates voltage gated Ca(2+) channel subtypes in sensory neurons after nerve injury

Loss of high-voltage–activated (HVA) calcium current (I(Ca)) and gain of low-voltage–activated (LVA) I(Ca) after painful peripheral nerve injury cause elevated excitability in sensory neurons. Nerve injury is also accompanied by increased expression of the extracellular matrix glycoprotein thrombosp...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Pan, Bin, Guo, Yuan, Wu, Hsiang-En, Park, John, Trinh, Van Nancy, Luo, Z. David, Hogan, Quinn H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988923/
https://ncbi.nlm.nih.gov/pubmed/27168360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000612
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