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Sigma-1 Receptor Antagonism Restores Injury-Induced Decrease of Voltage-Gated Ca(2+) Current in Sensory Neurons
Sigma-1 receptor (σ1R), an endoplasmic reticulum–chaperone protein, can modulate painful response after peripheral nerve injury. We have demonstrated that voltage-gated calcium current is inhibited in axotomized sensory neurons. We examined whether σ1R contributes to the sensory dysfunction of volta...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109486/ https://ncbi.nlm.nih.gov/pubmed/24891452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.214320 |
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