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α(2)-Adrenergic receptor and isoflurane modulation of presynaptic Ca(2+) influx and exocytosis in hippocampal neurons
BACKGROUND: Evidence indicates that the anesthetic-sparing effects of α(2)-adrenergic receptor (AR) agonists involve α(2A)-AR heteroreceptors on non-adrenergic neurons. Since volatile anesthetics inhibit neurotransmitter release by reducing synaptic vesicle (SV) exocytosis, we hypothesized that α(2)...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988866/ https://ncbi.nlm.nih.gov/pubmed/27337223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001213 |
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