Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones

BACKGROUND: P/Q- and N-type voltage-gated calcium channels (VGCC) are the principal subtypes mediating synaptic vesicle (SV) exocytosis. Both the degree of isoflurane inhibition of SV exocytosis and VGCC subtype expression vary between brain regions and neurotransmitter phenotype. We hypothesised th...

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Dades bibliogràfiques
Publicat a:Br J Anaesth
Autors principals: Koyanagi, Yuko, Torturo, Christina L., Cook, Daniel C., Zhou, Zhenyu, Hemmings, Hugh C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Neuroscience and Neuroanaesthesia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676046/
https://ncbi.nlm.nih.gov/pubmed/31056238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2019.03.029
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