AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

Inflammasomes are critical sensors that convey cellular stress and pathogen presence to the immune system by activating inflammatory caspases and cytokines such as IL-1β. The nature of endogenous stress signals that activate inflammasomes remains unclear. Here we show that an inhibitor of the HIV as...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Di Micco, Antonia, Frera, Gianluca, Lugrin, Jérôme, Jamilloux, Yvan, Hsu, Erh-Ting, Tardivel, Aubry, De Gassart, Aude, Zaffalon, Léa, Bujisic, Bojan, Siegert, Stefanie, Quadroni, Manfredo, Broz, Petr, Henry, Thomas, Hrycyna, Christine A., Martinon, Fabio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987819/
https://ncbi.nlm.nih.gov/pubmed/27462105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602419113
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