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On the origin and evolutionary consequences of gene body DNA methylation

In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively expressed genes (gene body methylation; gbM), but the origin and function of gbM remain unknown. Here we report the discovery that Eutrema salsugineum has lost gbM from its genome, to our knowledge the first...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Bewick, Adam J., Ji, Lexiang, Niederhuth, Chad E., Willing, Eva-Maria, Hofmeister, Brigitte T., Shi, Xiuling, Wang, Li, Lu, Zefu, Rohr, Nicholas A., Hartwig, Benjamin, Kiefer, Christiane, Deal, Roger B., Schmutz, Jeremy, Grimwood, Jane, Stroud, Hume, Jacobsen, Steven E., Schneeberger, Korbinian, Zhang, Xiaoyu, Schmitz, Robert J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987809/
https://ncbi.nlm.nih.gov/pubmed/27457936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604666113
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