On the origin and evolutionary consequences of gene body DNA methylation

In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively expressed genes (gene body methylation; gbM), but the origin and function of gbM remain unknown. Here we report the discovery that Eutrema salsugineum has lost gbM from its genome, to our knowledge the first...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bewick, Adam J., Ji, Lexiang, Niederhuth, Chad E., Willing, Eva-Maria, Hofmeister, Brigitte T., Shi, Xiuling, Wang, Li, Lu, Zefu, Rohr, Nicholas A., Hartwig, Benjamin, Kiefer, Christiane, Deal, Roger B., Schmutz, Jeremy, Grimwood, Jane, Stroud, Hume, Jacobsen, Steven E., Schneeberger, Korbinian, Zhang, Xiaoyu, Schmitz, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987809/
https://ncbi.nlm.nih.gov/pubmed/27457936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604666113
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